mens health 34

However, a research team from the Harvard Stem Cell Institute (HSCI), Harvard Medical School (HMS), and the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard has found that as stem cell lines grow in a lab dish, they often acquire mutations in the TP53 (p53) gene, an important tumor suppressor responsible for controlling cell growth and division. Their research suggests that genetic sequencing technologies should be used to screen for mutated cells in stem cell cultures, so that cultures with mutated cells can be excluded from scientific experiments and clinical therapies. If such methods are not employed it could lead to an elevated cancer risk in those receiving transplants. The paper, published online in the journal  Nature  on April, 26, comes at just the right time, the researchers said, as experimental treatments using human pluripotent stem cells are ramping up across the country. "Our results underscore the need for the field of ...

A mouse tibia that has been rendered clear with Bone CLARITY. Stem cells seem distributed all through the bone in purple. The flexibility to see bone stem cell conduct is essential for testing new osteoporosis remedies. Credit score: Science Translational Medication , Greenbaum, Chan, et al; Gradinaru laboratory/Caltech Ten years in the past, the bones presently in your physique didn't truly exist. Like pores and skin, bone is continually renewing itself, shedding previous tissue and rising it anew from stem cells within the bone marrow. Now, a brand new method developed at Caltech can render intact bones clear, permitting researchers to look at these stem cells inside their setting. The strategy is a breakthrough for testing new medication to fight illnesses like osteoporosis . The analysis was achieved within the laboratory of Viviana Gradinaru (BS '05), assistant professor of biology and organic engine...